Inserting eyedrops may seem difficult at first but becomes easier with practice. To put in an eyedrop, tilt the head back. Then create a pocket in front of the eye by pulling the lower lid down with an index finger or gently pinch the lower lid outward with the thumb and index finger. Let the drop fall into the pocket without touching your eye or eyelid (to prevent contamination of the bottle).
Immediately after instilling the drop, squeeze the bridge of your nose for two to three minutes with your thumb and forefinger. This prevents most of the drop from traveling down the tear duct to the rest of the body.
Keep your eyes closed for three to five minutes after instilling the drop. Because the volume of a single drop exceeds the capacity of the surface of the eye, it serves no purpose to use two drops at the same time.
Before opening your eyes, dab unabsorbed drops and tears from the closed lids with a tissue.
If you are taking two different types of eye drops, wait at least five minutes before instilling the second drop.